LABU vs XBI overlap - what they share and where they differ

LABU and XBI share 76.5% of their weight across 137 common positions, read from what each fund reported to the SEC.

Each week Ploutos reads the reported positions of the largest US equity ETFs and measures, pair by pair, the weight they share: for every stock both funds hold, the smaller of the two weights counts. Two funds tracking the same index land near 100%. A sector fund inside a broad index fund lands at roughly that sector's weight.

LABU and XBI

76.5%

137 shared positions

LABU

Direxion Daily S&P Biotech Bull 3X Shares

Reported positions cover 82% of the fund, 145 positions · Apr 30, 2026

Top 10: 12.2%·Holdings of LABU

XBI

State Street(R) SPDR(R) S&P(R) Biotech ETF

Reported positions cover 100% of the fund, 149 positions · Jun 30, 2026

Top 10: 13.3%·Holdings of XBI

Reported positions cover LABU 82%, XBI 100% of each fund. An overlap cannot exceed the smaller coverage, so a low figure can mean little overlap or thin reporting.

XBI vs LABU side by side

LABUDirexion Daily S&P Biotech Bull 3X Shares

145

stock positions reported to the SEC

3.8% of its weight is in 8 names XBI does not hold

XBIState Street(R) SPDR(R) S&P(R) Biotech ETF

149

stock positions reported to the SEC

2.8% of its weight is in 12 names LABU does not hold

Where each fund's weight sits

LABU
XBI
shared with the other fundheld alonenot covered by the filing (cash, futures, bonds)

Largest sectors for both funds

Healthcare
76.6%
95.7%
Basic Materials
1.1%
1.9%
Financial Services
0.2%
0.5%

The widest gap is Healthcare: XBI has 19.1 points more of it.

The figures side by side

LABUXBI
Filing dateApr 30, 2026Jun 30, 2026
Stock positions reported145149
Weight of the ten largest12.2%13.3%
Largest positionAPELLIS PHARMACEUTICALS INC 1.5%APGE 1.5%
Held alone8 positions, 3.8%12 positions, 2.8%
Covered by stock positions82%100%

Holdings they share

StockIn LABUIn XBICounted
RVMDRevolution Medicines Inc1.35%1.20%1.20%
TWSTTwist Bioscience Corporation1.17%1.41%1.17%
TVTXTravere Therapeutics Inc1.33%1.13%1.13%
ALKSAlkermes PLC1.14%1.11%1.11%
TGTXTG Therapeutics Inc1.13%1.09%1.09%
BEAMBeam Therapeutics Inc.1.09%1.08%1.08%
ARWRARROWHEAD PHARMACEUTICALS INC1.18%1.07%1.07%
MDGLMadrigal Pharmaceuticals Inc1.12%1.06%1.06%
APGEApogee Therapeutics Inc.1.04%1.49%1.04%
SMMTSummit Therapeutics Inc.1.15%1.01%1.01%

What each holds alone

The heaviest positions one fund reports and the other does not.

Only in LABU

APELLIS PHARMACEUTICALS INC1.53%
SOLENO THERAPEUTICS INC0.87%
CATALYST PHARMACEUTICALS INC.0.70%
KALVISTA PHARMACEUTICALS INC0.32%
AVXLAnavex Life Sciences Corp.0.10%
RCKTROCKET PHARMACEUTICALS INC0.10%
AKBAAkebia Therapeutics Inc.0.09%
IVVDInvivyd Inc0.09%

Only in XBI

CATALYST PHARMACEUTICALS INC0.87%
AVTXAvalo Therapeutics Inc0.35%
JBIOJade Biosciences Inc0.32%
SLDBSolid Biosciences Inc0.24%
IMMXImmix Biopharma Inc0.20%
CADLCandel Therapeutics Inc0.19%
MPLTMapLight Therapeutics Inc0.17%
CABACabaletta Bio Inc0.15%
OVIDOvid therapeutics Inc0.12%
ACHVAchieve Life Sciences Inc0.08%

Questions people ask

Is LABU the same as XBI?

76.5% of their weight sits in the same 137 holdings. LABU also reports APELLIS PHARMACEUTICALS INC, SOLENO THERAPEUTICS INC, CATALYST PHARMACEUTICALS INC., which the other does not. XBI also reports CATALYST PHARMACEUTICALS INC, AVTX, JBIO, which the other does not.

How is the overlap between LABU and XBI measured?

For every stock both funds report, the smaller of the two weights counts, and the sum is the overlap. The reported positions cover 82% of LABU and 100% of XBI, so the number cannot exceed the smaller coverage.

Which holds more, XBI or LABU?

LABU reports 145 stock positions and XBI reports 149. 3.8% of LABU's weight sits in names XBI does not hold, and 2.8% of XBI's weight in names LABU does not hold. The ten largest positions are 12.2% of LABU and 13.3% of XBI.

How do LABU and XBI differ by sector?

The widest gap is Healthcare: XBI has 19.1 points more of it. Sectors come from each holding's SIC code in its SEC record, summed by the weight the fund reports.

Where do the numbers come from?

From each fund's own N-PORT filing to the SEC, which lists every position and its weight. The comparison uses every equity position the fund reports; cash, futures and bonds are not counted, which is why a coverage figure sits next to every result. Holdings change between filings.

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Descriptive data from public SEC filings. Nothing on this page is a recommendation to buy, sell or hold any fund or stock, and holdings change between filings.