LABU holdings - what the fund actually owns
Direxion Daily S&P Biotech Bull 3X Shares reports 147 stock positions to the SEC, 67% of its assets. The ten largest are 9.4% of the fund, as of Jul 31, 2026.
Each week Ploutos reads the latest N-PORT filing of the largest US equity ETFs. This page is one fund's filing: its reported positions with their weights, where that weight sits by sector, what entered and left since the previous filing, and which other funds hold the most of the same stocks.
Reported positions
147
cover 67% of the fund
Weight of the top 10 holdings
9.4%
of the fund in ten names
Largest position
APOGEE THERAPEUTICS INC
1.11% · APOGEE THERAPEUTICS INC
Filing date
Jul 31, 2026
holdings as reported to the SEC
Where the weight sits, by sector
Sectors come from each company's industry code in its SEC record, so they are coarse. 1.1% of the reported weight could not be placed and is shown as unknown.
Full holdings list, heaviest first
| # | Stock | Weight | Cumulative |
|---|---|---|---|
| 1 | APOGEE THERAPEUTICS INC | 1.11% | 1.1% |
| 2 | ORKAORUKA THERAPEUTICS INC | 1.03% | 2.1% |
| 3 | DNTHDIANTHUS THERAPEUTICS INC | 0.96% | 3.1% |
| 4 | ERASERASCA INC | 0.93% | 4.0% |
| 5 | TWSTTWIST BIOSCIENCE CORP | 0.92% | 4.9% |
| 6 | KYMRKYMERA THERAPEUTICS INC | 0.90% | 5.8% |
| 7 | SYRESPYRE THERAPEUTICS INC | 0.89% | 6.7% |
| 8 | RVMDREVOLUTION MEDICINES INC | 0.89% | 7.6% |
| 9 | CGONCG ONCOLOGY INC | 0.88% | 8.5% |
| 10 | PTGXPROTAGONIST THERAPEUTICS INC | 0.88% | 9.4% |
| 11 | PRAXPRAXIS PRECISION MEDICINES INC | 0.87% | 10.3% |
| 12 | REGNREGENERON PHARMACEUTICALS INC | 0.87% | 11.1% |
| 13 | COGTCOGENT BIOSCIENCES INC | 0.85% | 12.0% |
| 14 | NTRANATERA INC | 0.84% | 12.8% |
| 15 | ARWRARROWHEAD PHARMACEUTICALS INC | 0.82% | 13.6% |
| 16 | TVTXTRAVERE THERAPEUTICS INC | 0.82% | 14.5% |
| 17 | ROIVROIVANT SCIENCES LTD | 0.81% | 15.3% |
| 18 | RLAYRELAY THERAPEUTICS INC | 0.81% | 16.1% |
| 19 | MRNAMODERNA INC | 0.81% | 16.9% |
| 20 | PCVXVAXCYTE INC | 0.81% | 17.7% |
| 21 | BBIOBRIDGEBIO PHARMA INC | 0.81% | 18.5% |
| 22 | HALOHALOZYME THERAPEUTICS INC | 0.80% | 19.3% |
| 23 | RYTMRHYTHM PHARMACEUTICALS INC | 0.79% | 20.1% |
| 24 | CYTKCYTOKINETICS INC | 0.79% | 20.9% |
| 25 | VKTXVIKING THERAPEUTICS INC | 0.78% | 21.7% |
| 26 | AMGNAMGEN INC | 0.78% | 22.5% |
| 27 | INCYINCYTE CORP | 0.77% | 23.2% |
| 28 | MIRMMIRUM PHARMACEUTICALS INC | 0.77% | 24.0% |
| 29 | ALKSALKERMES PLC | 0.76% | 24.8% |
| 30 | TGTXTG THERAPEUTICS INC | 0.76% | 25.5% |
| 31 | ABBVABBVIE INC | 0.76% | 26.3% |
| 32 | VRTXVERTEX PHARMACEUTICALS INC | 0.75% | 27.0% |
| 33 | KRYSKRYSTAL BIOTECH INC | 0.75% | 27.8% |
| 34 | INSMINSMED INC | 0.73% | 28.5% |
| 35 | SRRKSCHOLAR ROCK HOLDING CORP | 0.73% | 29.2% |
| 36 | GILDGILEAD SCIENCES INC | 0.73% | 30.0% |
| 37 | BMRNBIOMARIN PHARMACEUTICAL INC | 0.73% | 30.7% |
| 38 | QUREUNIQURE NV | 0.72% | 31.4% |
| 39 | DYNDYNE THERAPEUTICS INC | 0.72% | 32.1% |
| 40 | BIIBBIOGEN INC | 0.71% | 32.8% |
| 41 | NBIXNEUROCRINE BIOSCIENCES INC | 0.71% | 33.6% |
| 42 | ACADACADIA PHARMACEUTICALS INC | 0.71% | 34.3% |
| 43 | EXELEXELIXIS INC | 0.69% | 34.9% |
| 44 | IMVTIMMUNOVANT INC | 0.68% | 35.6% |
| 45 | MDGLMADRIGAL PHARMACEUTICALS INC | 0.68% | 36.3% |
| 46 | GRALGRAIL INC | 0.67% | 37.0% |
| 47 | CELCCELCUITY INC | 0.67% | 37.6% |
| 48 | SMMTSUMMIT THERAPEUTICS INC | 0.67% | 38.3% |
| 49 | CRSPCRISPR THERAPEUTICS AG | 0.66% | 39.0% |
| 50 | UTHRUNITED THERAPEUTICS CORP | 0.65% | 39.6% |
| 51 | PTCTPTC THERAPEUTICS INC | 0.63% | 40.3% |
| 52 | RAREULTRAGENYX PHARMACEUTICAL INC | 0.63% | 40.9% |
| 53 | IBRXIMMUNITYBIO INC | 0.61% | 41.5% |
| 54 | SLSSELLAS LIFE SCIENCES GROUP INC | 0.59% | 42.1% |
| 55 | BEAMBEAM THERAPEUTICS INC | 0.59% | 42.7% |
| 56 | BCRXBIOCRYST PHARMACEUTICALS INC | 0.59% | 43.3% |
| 57 | VERAVERA THERAPEUTICS INC | 0.58% | 43.9% |
| 58 | IDYAIDEAYA BIOSCIENCES INC | 0.56% | 44.4% |
| 59 | DNLIDENALI THERAPEUTICS INC | 0.55% | 45.0% |
| 60 | TNGXTANGO THERAPEUTICS INC | 0.54% | 45.5% |
| 61 | ARQTARCUTIS BIOTHERAPEUTICS INC | 0.54% | 46.0% |
| 62 | CLDXCELLDEX THERAPEUTICS INC | 0.53% | 46.6% |
| 63 | VRDNVIRIDIAN THERAPEUTICS INC | 0.51% | 47.1% |
| 64 | IRONDISC MEDICINE INC | 0.51% | 47.6% |
| 65 | RCUSARCUS BIOSCIENCES INC | 0.50% | 48.1% |
| 66 | MLYSMINERALYS THERAPEUTICS INC | 0.49% | 48.6% |
| 67 | IONSIONIS PHARMACEUTICALS INC | 0.48% | 49.1% |
| 68 | ALNYALNYLAM PHARMACEUTICALS INC | 0.48% | 49.5% |
| 69 | VCYTVERACYTE INC | 0.48% | 50.0% |
| 70 | IMNMIMMUNOME INC | 0.47% | 50.5% |
| 71 | SNDXSYNDAX PHARMACEUTICALS INC | 0.46% | 50.9% |
| 72 | RXRXRECURSION PHARMACEUTICALS INC | 0.46% | 51.4% |
| 73 | SRPTSAREPTA THERAPEUTICS INC | 0.45% | 51.9% |
| 74 | ADMAADMA BIOLOGICS INC | 0.45% | 52.3% |
| 75 | KODKODIAK SCIENCES INC | 0.43% | 52.7% |
| 76 | NTLAINTELLIA THERAPEUTICS INC | 0.42% | 53.2% |
| 77 | AGIOAGIOS PHARMACEUTICALS INC | 0.41% | 53.6% |
| 78 | IOVAIOVANCE BIOTHERAPEUTICS INC | 0.41% | 54.0% |
| 79 | NRIXNURIX THERAPEUTICS INC | 0.39% | 54.4% |
| 80 | PVLAPALVELLA THERAPEUTICS INC | 0.39% | 54.8% |
| 81 | NVAXNOVAVAX INC | 0.38% | 55.1% |
| 82 | VCELVERICEL CORP | 0.38% | 55.5% |
| 83 | BHVNBIOHAVEN LTD | 0.35% | 55.9% |
| 84 | CDNACAREDX INC | 0.34% | 56.2% |
| 85 | STOKSTOKE THERAPEUTICS INC | 0.31% | 56.5% |
| 86 | PGENPRECIGEN INC | 0.31% | 56.8% |
| 87 | TYRATYRA BIOSCIENCES INC | 0.31% | 57.1% |
| 88 | VIRVIR BIOTECHNOLOGY INC | 0.29% | 57.4% |
| 89 | ZBIOZENAS BIOPHARMA INC | 0.29% | 57.7% |
| 90 | ANABANAPTYSBIO INC | 0.29% | 58.0% |
| 91 | TRAXFIRST TRACKS BIOTHERAPEUTICS INC | 0.28% | 58.3% |
| 92 | ABSIABSCI CORP | 0.28% | 58.6% |
| 93 | PURRHYPERLIQUID STRATEGIES INC | 0.27% | 58.8% |
| 94 | CGEMCULLINAN THERAPEUTICS INC | 0.27% | 59.1% |
| 95 | XNCRXENCOR INC | 0.27% | 59.4% |
| 96 | CRVSCORVUS PHARMACEUTICALS INC | 0.27% | 59.6% |
| 97 | VORVOR BIOPHARMA INC | 0.26% | 59.9% |
| 98 | AVTXAVALO THERAPEUTICS INC | 0.25% | 60.1% |
| 99 | ARDXARDELYX INC | 0.25% | 60.4% |
| 100 | ORICORIC PHARMACEUTICALS INC | 0.25% | 60.6% |
| 101 | GLUEMONTE ROSA THERAPEUTICS INC | 0.24% | 60.9% |
| 102 | MNKDMANNKIND CORP | 0.23% | 61.1% |
| 103 | INBXINHIBRX BIOSCIENCES INC | 0.23% | 61.3% |
| 104 | TSHATAYSHA GENE THERAPIES INC | 0.22% | 61.6% |
| 105 | ANNXANNEXON INC | 0.22% | 61.8% |
| 106 | OLMAOLEMA PHARMACEUTICALS INC | 0.21% | 62.0% |
| 107 | REPLREPLIMUNE GROUP INC | 0.21% | 62.2% |
| 108 | SIONSIONNA THERAPEUTICS INC | 0.21% | 62.4% |
| 109 | JBIOJADE BIOSCIENCES INC | 0.21% | 62.6% |
| 110 | BCAXBICARA THERAPEUTICS INC | 0.20% | 62.8% |
| 111 | JANXJANUX THERAPEUTICS INC | 0.20% | 63.0% |
| 112 | GERNGERON CORP | 0.19% | 63.2% |
| 113 | KURAKURA ONCOLOGY INC | 0.19% | 63.4% |
| 114 | AVBPARRIVENT BIOPHARMA INC | 0.18% | 63.6% |
| 115 | CTMXCYTOMX THERAPEUTICS INC | 0.17% | 63.8% |
| 116 | RIGLRIGEL PHARMACEUTICALS INC | 0.16% | 63.9% |
| 117 | IRWDIRONWOOD PHARMACEUTICALS INC | 0.16% | 64.1% |
| 118 | ALTALTIMMUNE INC | 0.16% | 64.2% |
| 119 | ALLOALLOGENE THERAPEUTICS INC | 0.16% | 64.4% |
| 120 | SANASANA BIOTECHNOLOGY INC | 0.15% | 64.6% |
| 121 | SLDBSOLID BIOSCIENCES INC | 0.14% | 64.7% |
| 122 | DMRADAMORA THERAPEUTICS INC | 0.14% | 64.8% |
| 123 | CADLCANDEL THERAPEUTICS INC | 0.14% | 65.0% |
| 124 | VSTMVERASTEM INC | 0.14% | 65.1% |
| 125 | RGNXREGENXBIO INC | 0.13% | 65.2% |
| 126 | IMMXIMMIX BIOPHARMA INC | 0.12% | 65.4% |
| 127 | SVRASAVARA INC | 0.12% | 65.5% |
| 128 | OCGNOCUGEN INC | 0.12% | 65.6% |
| 129 | FDMT4D MOLECULAR THERAPEUTICS INC | 0.11% | 65.7% |
| 130 | ABUSARBUTUS BIOPHARMA CORP | 0.11% | 65.8% |
| 131 | PRMEPRIME MEDICINE INC | 0.10% | 65.9% |
| 132 | CABACABALETTA BIO INC | 0.10% | 66.0% |
| 133 | CMPXCOMPASS THERAPEUTICS INC | 0.09% | 66.1% |
| 134 | EBSEMERGENT BIOSOLUTIONS INC | 0.08% | 66.2% |
| 135 | MDXGMIMEDX GROUP INC | 0.08% | 66.3% |
| 136 | PRTAPROTHENA CORP PLC | 0.08% | 66.4% |
| 137 | CATXPERSPECTIVE THERAPEUTICS INC | 0.08% | 66.5% |
| 138 | SPRYARS PHARMACEUTICALS INC | 0.08% | 66.5% |
| 139 | VNDAVANDA PHARMACEUTICALS INC | 0.08% | 66.6% |
| 140 | OVIDOVID THERAPEUTICS INC | 0.08% | 66.7% |
| 141 | LXEOLEXEO THERAPEUTICS INC | 0.07% | 66.8% |
| 142 | ACHVACHIEVE LIFE SCIENCES INC | 0.06% | 66.8% |
| 143 | MYGNMYRIAD GENETICS INC | 0.06% | 66.9% |
| 144 | CAPRCAPRICOR THERAPEUTICS INC | 0.06% | 66.9% |
| 145 | SGMTSAGIMET BIOSCIENCES INC | 0.05% | 67.0% |
| 146 | BBOTBRIDGEBIO ONCOLOGY THERAPEUTICS INC | 0.05% | 67.0% |
| 147 | MPLTMAPLIGHT THERAPEUTICS INC | 0.04% | 67.1% |
What changed since the Apr 30, 2026 filing
Entered the reported positions
Left the reported positions
Entered means the name is among the reported top positions now and was not in the previous filing. That can be a purchase or a rise in weight, and the filing does not say which.
Funds that hold the most of the same stocks
The share of LABU that is also in each fund, from the positions both report. Open a fund for its own page, or the overlap figure to compare the two.
| Fund | Overlap | Shared |
|---|---|---|
| XBIState Street(R) SPDR(R) S&P(R) Biotech ETF | 66.9% | 147 |
| IBBiShares Biotechnology ETF | 35.5% | 121 |
| IWOiShares Russell 2000 Growth ETF | 13.5% | 100 |
| VHTVANGUARD HEALTH CARE INDEX FUND | 11.5% | 122 |
| VBKVANGUARD SMALL-CAP GROWTH INDEX FUND | 9.9% | 43 |
| IYHiShares U.S. Healthcare ETF | 9.3% | 24 |
| IWMiShares Russell 2000 ETF | 9.1% | 121 |
| VTWOVANGUARD RUSSELL 2000 INDEX FUND | 7.3% | 109 |
Questions people ask
What are the top holdings of LABU?
Its filing lists 147 stock positions. The largest are APOGEE THERAPEUTICS INC 1.1%, ORKA 1.0%, DNTH 1.0%, and the ten largest together are 9.4% of the fund. The full list with weights is on this page.
How many stocks are in LABU?
LABU reports 147 stock positions in its SEC filing of Jul 31, 2026, and together they are 67% of the fund. Cash, futures and bonds the fund holds are not counted.
How do I check whether LABU holds a particular stock?
Search the full list on this page by ticker or company name, for example NVDA or Nvidia. A stock the fund holds shows with its weight and its rank in the fund. If it does not show, the fund did not report it as a position in this filing.
How often do these holdings change?
Funds report their positions to the SEC at each quarter end, and the SEC publishes the filing about 60 days later. Ploutos reads the latest one every week, so the page changes four times a year, and shows the date of the filing it reads.
Why does the coverage not reach 100%?
The list is the stock positions the fund reports. Cash, futures, bonds and other assets the filing carries are not listed, and what the stocks add up to is the coverage shown. A stock fund lands near 100; a fund that holds futures or a cash sleeve lands lower. Weights are of the whole fund.
Compare LABU with another fund·All fund pairs
Descriptive data from public SEC filings. Nothing on this page is a recommendation to buy, sell or hold any fund or stock, and holdings change between filings.